Leucovorin and Fluorouracil With or Without Oxaliplatin as First-Line Treatment in Advanced Colorectal Cancer

de Gramont, Aimery; Figer, Arié; Seymour, Michel; Homerin, M.; Hmissi, Abdel; Cassidy, Jim; Boni, C.; Cortés-Funes, H.; Cervantes, Andrés; Freyer, Gilles; Papamichael, D.; Le Bail, N; Louvet, Christophe; Hendler, Daniel; de Braud, Filippo; Wilson, C.; Morvan, F.; Bonetti, Andrea

doi:10.1200/jco.2000.18.16.2938

Public

Leucovorin and Fluorouracil With or Without Oxaliplatin as First-Line Treatment in Advanced Colorectal Cancer

Published in Journal of Clinical Oncology • Aug 16, 2000

Authors:

Aimery de Gramont

Arié Figer

Michel Seymour

Abstract

PURPOSE: In a previous study of treatment for advanced colorectal cancer, the LV5FU2 regimen, comprising leucovorin (LV) plus bolus and infusional fluorouracil (5FU) every 2 weeks, was superior to the standard North Central Cancer Treatment Group/Mayo Clinic 5-day bolus 5FU/LV regimen. This phase II...

Subject

Medicine

Oxaliplatin

Fluorouracil

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