The Long-Term Effect of Doxazosin, Finasteride, and Combination Therapy on the Clinical Progression of Benign Prostatic Hyperplasia

D. McConnell, John; G. Roehrborn, Claus; Bautista, Oliver; L. Andriole, Gerald; Dixon, Christopher; W. Kusek, John; Lepor, Herbert; T. McVary, Kevin; M. Nyberg, Leroy; S. Clarke, Harry; David Crawford, E.; C. Diokno, Ananias; P. Foley, John; E. Foster, Harris; C. Jacobs, Stephen; A. Kaplan, Steven; J. Kreder, Karl; M. Lieber, Michael; Scott Lucia, M.; J. Miller, Gary; Menon, Mani; F. Milam, Douglas; Ramsdell, Joe; S. Schenkman, Noah; M. Slawin, Kevin; A. Smith, Joseph

doi:10.1056/nejmoa030656

Public

The Long-Term Effect of Doxazosin, Finasteride, and Combination Therapy on the Clinical Progression of Benign Prostatic Hyperplasia

Published in New England Journal of Medicine • Dec 17, 2003

Authors:

John D. McConnell

Claus G. Roehrborn

Oliver Bautista

Abstract

BACKGROUND: Benign prostatic hyperplasia is commonly treated with alpha-adrenergic-receptor antagonists (alpha-blockers) or 5alpha-reductase inhibitors. The long-term effect of these drugs, singly or combined, on the risk of clinical progression is unknown. METHODS: We conducted a long-term, double-...

Subject

Doxazosin

Finasteride

Medicine

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