Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians

Li, Haipeng; O. Kilpeläinen, Tuomas; Liu, Chaolei; Zhu, Jingwen; Liu, Yu; Hu, Cheng; Yang, Zhen; Zhang, W.; Bao, W.; Cha, Seongwon; Wu, Yuping; Yang, Tie‐Lin; Sekine, Akihiro; Youl Choi, Bo; S. Yajnik, Chittaranjan; Zhou, Daizhan; Takeuchi, Fumihiko; Yamamoto, Ken; C.N. Chan, Juliana; Radha Mani, K.; Been, Latonya; Imamura, Minako; Nakashima, Eitaro; Lee, N.; Fujisawa, Tomomi; Karasawa, Shigeru; Wen, Wanqing; Joglekar, Charudatta; Lu, Wei; Chang, Yi‐Cheng; Xiang, Yong‐Bing; Gao, Y.-T.; Liu, Simin; Song, Yijun; Heon Kwak, Soo; Doo Shin, Hyoung; Soo Park, Kyong; Fall, Caroline; Y. Kim, J.; C. Sham, Pak; S.L. Lam, Karen; Zheng, Weiwei; Shu, Xiao‐Ou; Deng, Hong‐Wen; Ikegami, Hiroshi; V. Krishnaveni, Ghattu; K. Sanghera, Dharambir; Chuang, Lee‐Ming; Liu, L.; Hu, Renming; Kim, Youngjo; Daimon, Makoto; Hotta, Kikuko; Jia, Wei; S. Kooner, Jaspal; C. Chambers, John; R. Chandak, Giriraj; C. Ma, R.; Maeda, Shiro; Dorajoo, Rajkumar; Yokota, Mitsuhiro; Takayanagi, R.; Kato, Norihiro; Lin, Xu; J. F. Loos, Ruth

doi:10.1007/s00125-011-2370-7

Public

Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians

Published in Diabetologia • Nov 22, 2011

Authors:

Haipeng Li

Tuomas O. Kilpeläinen

Chaolei Liu

Abstract

AIMS/HYPOTHESIS: FTO harbours the strongest known obesity-susceptibility locus in Europeans. While there is growing evidence for a role for FTO in obesity risk in Asians, its association with type 2 diabetes, independently of BMI, remains inconsistent. To test whether there is an association of the ...

Subject

Type 2 diabetes

Human physiology

Obesity

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