Prospective comparison of autologous stem cell transplantation followed by dose-reduced allograft (IFM99-03 trial) with tandem autologous stem cell transplantation (IFM99-04 trial) in high-risk de novo multiple myeloma

Garban, Frédéric; Attal, Michel; Michallet, Mauricette; Hulin, Cyrille; Henri Bourhis, Jean; Yakoub‐Agha, Ibrahim; Lamy, Thierry; Marit, Gérald; Maloisel, Frédéric; Berthou, Christian; Dib, Mamoun; Caillot, Denis; Deprijck, Bernard; Ketterer, Nicolas; Harousseau, Jean‐Luc; Sotto, Jean‐Jacques; Moreau, Philippe

doi:10.1182/blood-2005-09-3869

Public

Prospective comparison of autologous stem cell transplantation followed by dose-reduced allograft (IFM99-03 trial) with tandem autologous stem cell transplantation (IFM99-04 trial) in high-risk de novo multiple myeloma

Published in Blood • Jan 5, 2006

Authors:

Frédéric Garban

Michel Attal

Mauricette Michallet

Abstract

The Intergroupe Francophone du Myélome (IFM) initiated 2 trials in 1999 to study patients with high-risk (beta2-microglobulin level greater than 3 mg/L and chromosome 13 deletion at diagnosis) de novo multiple myeloma. In both protocols, the induction regimen consisted of vincristine, doxorubicin, a...

Subject

Medicine

Melphalan

Transplantation

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