Which Pneumococcal Serogroups Cause the Most Invasive Disease: Implications for Conjugate Vaccine Formulation and Use, Part I

P. Hausdorff, William; Bryant, John; R. Paradiso, Peter; R. Siber, George

doi:10.1086/313608

Public

Which Pneumococcal Serogroups Cause the Most Invasive Disease: Implications for Conjugate Vaccine Formulation and Use, Part I

Published in Clinical Infectious Diseases • Jan 1, 2000

Authors:

William P. Hausdorff

John Bryant

Peter R. Paradiso

Abstract

We analyzed >70 recent data sets to compare the serogroups causing invasive pneumococcal disease (IPD) with those represented in conjugate vaccine formulations. Five to 8 and 10-11 serogroups comprise at least 75% of pneumococcal isolates from young children and older children/adults, respectively, ...

Subject

Medicine

Pneumococcal disease

Pneumococcal conjugate vaccine

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