Noroviruses Bind to Human ABO, Lewis, and Secretor Histo–Blood Group Antigens: Identification of 4 Distinct Strain‐Specific Patterns

Huang, Pengwei; Farkas, Tibor; Marionneau‐Lambot, Séverine; Zhong, Weiming; Ruvoën‐Clouet, Nathalie; L. Morrow, Ardythe; Altaye, Mekibib; K. Pickering, Larry; S. Newburg, David; LePendu, Jacques; Jiang, Xi

doi:10.1086/375742

Public

Noroviruses Bind to Human ABO, Lewis, and Secretor Histo–Blood Group Antigens: Identification of 4 Distinct Strain‐Specific Patterns

Published in The Journal of Infectious Diseases • Jul 1, 2003

Authors:

Pengwei Huang

Tibor Farkas

Séverine Marionneau‐Lambot

Abstract

We characterized the binding of 8 Noroviruses (NORs) to histo-blood group antigens (HBGAs) in human saliva using recombinant NOR (rNOR) capsid proteins. Among the 8 rNORs tested, 6 formed viruslike particles (VLPs) when the capsid proteins were expressed in insect cells, all of which revealed variab...

Subject

ABO blood group system

Saliva

Capsid

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