A worldwide multicentre comparison of assays for cerebrospinal fluid biomarkers in Alzheimer's disease

A. Verwey, Nicolaas; M. van der Flier, Wiesje; Blennow, Kaj; M. Clark, Christopher; Sokolow, Sophie; Paul De Deyn, Peter; Galasko, Douglas; Hampel, Harald; Hartmann, Tobias; Kapaki, E.; Lannfelt, Lars; Mehta, Pankaj; Parnetti, Lucilla; Petzold, Axel; Pirttilä, Tuula; Saleh, Lanja; Skinningsrud, Anders; C. van Swieten, John; M. Verbeek, Marcel; Wiltfang, Jens; Younkin, Steve; Scheltens, Philip; A. Blankenstein, Marinus

doi:10.1258/acb.2009.008232

Public

A worldwide multicentre comparison of assays for cerebrospinal fluid biomarkers in Alzheimer's disease

Published in Annals of Clinical Biochemistry International Journal of Laboratory Medicine • Apr 2, 2009

Authors:

Nicolaas A. Verwey

Wiesje M. van der Flier

Kaj Blennow

Abstract

BACKGROUND: Different cerebrospinal fluid (CSF) amyloid-beta 1-42 (Abeta(1-42)), total Tau (Tau) and Tau phosphorylated at threonine 181 (P-Tau) levels are reported, but currently there is a lack of quality control programmes. The aim of this study was to compare the measurements of these CSF biomar...

Subject

Cerebrospinal fluid

Medicine

Amyloid β

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