Changes in antithrombin and fibrinogen levels during induction chemotherapy with L-asparaginase in adult patients with acute lymphoblastic leukemia or lymphoblastic lymphoma. Use of supportive coagulation therapy and clinical outcome: the CAPELAL study

Hunault, Mathilde; Chevallier, P.; Delain, Martine; Bulabois, C.-E.; Bologna, S.; Bernard, Marc; Lafon, Ingrid; Cornillon, Jérôme; Maakaroun, Abdallah; Tizon, A.; Padrazzi, Bruno; Ifrah, Norbert; Gruel, Yves; the GOELAMS (Groupe Ouest-Est des Leucemies Aigues et Maladies du Sang), for

doi:10.3324/haematol.12948

Public

Changes in antithrombin and fibrinogen levels during induction chemotherapy with L-asparaginase in adult patients with acute lymphoblastic leukemia or lymphoblastic lymphoma. Use of supportive coagulation therapy and clinical outcome: the CAPELAL study

Published in Haematologica • Aug 26, 2008

Authors:

Mathilde Hunault

P. Chevallier

Martine Delain

Abstract

BACKGROUND: The effects of L-asparaginase on hemostasis during induction chemotherapy are less defined in adults than in children. We, therefore, studied the effects of L-asparaginase in adult patients. DESIGN AND METHODS: This was a retrospective analysis of 214 patients treated with L-asparaginase...

Subject

Antithrombin

Medicine

Fibrinogen

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