Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA-peptide tetramers.

M, Cobbold; N, Khan; B, Pourgheysari; S, Tauro; D, McDonald; H, Osman; M, Assenmacher; L, Billingham; C, Steward; C, Crawley; E, Olavarria; J, Goldman; R, Chakraverty; P, Mahendra; C, Craddock; PA, Moss

doi:10.1084/jem.20040613

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Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA-peptide tetramers.

Shared by NobleBlocks on Aug 1, 2005 • 12:00 AM UTC

Authors:

Cobbold M

Khan N

Pourgheysari B

Abstract

Stem cell transplantation is used widely in the management of a range of diseases of the hemopoietic system. Patients are immunosuppressed profoundly in the early posttransplant period, and reactivation of cytomegalovirus (CMV) remains a significant cause of morbidity and mortality. Adoptive transfe...

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