Inflammatory Cytokine Concentrations Are Acutely Increased by Hyperglycemia in Humans

Esposito, Katherine; Nappo, Francesco; Marfella, Raffaele; Giugliano, Giovanni; Giugliano, Francesco; Ciotola, Myriam; Quagliaro, Lisa; Ceriello, Antonio; Giugliano, Dario

doi:10.1161/01.cir.0000034509.14906.ae

Public

Inflammatory Cytokine Concentrations Are Acutely Increased by Hyperglycemia in Humans

Published in Circulation • Oct 14, 2002

Authors:

Katherine Esposito

Francesco Nappo

Raffaele Marfella

Abstract

BACKGROUND: Circulating levels of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) are elevated in diabetic patients. We assessed the role of glucose in the regulation of circulating levels of IL-6, TNF-alpha, and interleukin-18 (IL-18) in subjects with normal or impaired glucose tol...

Subject

Medicine

Internal medicine

Endocrinology

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