Corneal Reconstruction with Tissue-Engineered Cell Sheets Composed of Autologous Oral Mucosal Epithelium

Nishida, Kohji; Yamato, Masayuki; Hayashida, Yasutaka; WATANABE, Katsuhiko; Yamamoto, Kazuaki; Adachi, Eijiro; Nagai, Shigeru; Kikuchi, Akihiko; Maeda, Naoyuki; Watanabe, Hitoshi; Okano, Teruo; Tano, Yasuo

doi:10.1056/nejmoa040455

Public

Corneal Reconstruction with Tissue-Engineered Cell Sheets Composed of Autologous Oral Mucosal Epithelium

Published in New England Journal of Medicine • Sep 15, 2004

Authors:

Kohji Nishida

Masayuki Yamato

Yasutaka Hayashida

Abstract

BACKGROUND: Ocular trauma or disease may lead to severe corneal opacification and, consequently, severe loss of vision as a result of complete loss of corneal epithelial stem cells. Transplantation of autologous corneal stem-cell sources is an alternative to allograft transplantation and does not re...

Subject

Medicine

Transplantation

Corneal epithelium

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