Folate, Methionine, and Alcohol Intake and Risk of Colorectal Adenoma

L. Giovannucci, Edward; J. Stampfer, Meir; A. Colditz, Graham; B. Rimm, Eric; Trichopoulos, D; A. Rosner, B.; E Speizer, F; C. Willett, Walter

doi:10.1093/jnci/85.11.875

Public

Folate, Methionine, and Alcohol Intake and Risk of Colorectal Adenoma

Published in JNCI Journal of the National Cancer Institute • Jun 2, 1993

Authors:

Edward L. Giovannucci

Meir J. Stampfer

Graham A. Colditz

Abstract

BACKGROUND: Reduced methylation of DNA may contribute to loss of the normal controls on proto-oncogene expression. In humans, hypomethylation of DNA has been observed in colorectal cancers and in their adenomatous polyp precursors. Accumulation of DNA methylation abnormalities, observed during progr...

Subject

Medicine

Colorectal cancer

Adenoma

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!