Plasma exchange and glucocorticoid dosing in the treatment of anti-neutrophil cytoplasm antibody associated vasculitis (PEXIVAS): protocol for a randomized controlled trial

Walsh, Michael; A. Merkel, Peter; Au Peh, Chen; Szpirt, Wladimir; Guillevin, Loı̈c; D. Pusey, Charles; de Zoysa, Janak; Ives, Natalie; F. Clark, William; Quillen, Karen; L. Winters, Jeffrey; Wheatley, Keith; Jayne, David; behalf of the PEXIVAS Investigators, on

doi:10.1186/1745-6215-14-73

Public

Plasma exchange and glucocorticoid dosing in the treatment of anti-neutrophil cytoplasm antibody associated vasculitis (PEXIVAS): protocol for a randomized controlled trial

Published in Trials • Jan 1, 2013

Authors:

Michael Walsh

Peter A. Merkel

Chen Au Peh

Abstract

BACKGROUND: Granulomatosis with polyangiitis (GPA, Wegener's) and microscopic polyangiitis (MPA) are small vessel vasculitides collectively referred to as anti-neutrophil cytoplasm antibody-associated vasculitis (AAV). AAV is associated with high rates of morbidity and mortality due to uncontrolled ...

Subject

Medicine

Randomized controlled trial

Microscopic polyangiitis

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