The genomic landscape of pediatric Ewing sarcoma.

BD, Crompton; C, Stewart; A, Taylor-Weiner; G, Alexe; KC, Kurek; ML, Calicchio; A, Kiezun; SL, Carter; SA, Shukla; SS, Mehta; AR, Thorner; Torres C, de; C, Lavarino; M, Suñol; A, McKenna; A, Sivachenko; K, Cibulskis; MS, Lawrence; P, Stojanov; M, Rosenberg; L, Ambrogio; D, Auclair; S, Seepo; B, Blumenstiel; M, DeFelice; I, Imaz-Rosshandler; Y Celis A, Schwarz-Cruz; MN, Rivera; C, Rodriguez-Galindo; MD, Fleming; TR, Golub; G, Getz; J, Mora; K, Stegmaier

doi:10.1158/2159-8290.cd-13-1037

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The genomic landscape of pediatric Ewing sarcoma.

Shared by NobleBlocks on Sep 3, 2014 • 12:00 AM UTC

Authors:

Crompton BD

Stewart C

Taylor-Weiner A

Abstract

Unlabelled Pediatric Ewing sarcoma is characterized by the expression of chimeric fusions of EWS and ETS family transcription factors, representing a paradigm for studying cancers driven by transcription factor rearrangements. In this study, we describe the somatic landscape of pediatric Ewing sarco...

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