The Genomic Landscape of Pediatric Ewing Sarcoma

D. Crompton, Brian; Stewart, Chip; Taylor‐Weiner, Amaro; Alexe, Gabriela; C. Kurek, Kyle; L. Calicchio, Monica; Kieżun, Adam; L. Carter, Scott; A. Shukla, Sachet; Mehta, Swapnil; R. Thorner, Aaron; de Torres, Carmen; Lavarino, Cinzia; Suñol, Mariona; McKenna, Aaron; Sivachenko, Andrey; Cibulskis, Kristian; S. Lawrence, Michael; Stojanov, Petar; Rosenberg, Mara; Ambrogio, Lauren; Auclair, Daniel; Seepo, Sara; Blumenstiel, Brendan; DeFelice, Matthew; Imaz-Rosshandler, Iván; Schwarz‐Cruz y Celis, Angela; N. Rivera, Miguel; Rodríguez‐Galindo, Carlos; D. Fleming, Mark; R. Golub, Todd; Getz, Gad; Mora, Jaume; Stegmaier, Kimberly

doi:10.1158/2159-8290.cd-13-1037

Public

The Genomic Landscape of Pediatric Ewing Sarcoma

Published in Cancer Discovery • Sep 4, 2014

Authors:

Brian D. Crompton

Chip Stewart

Amaro Taylor‐Weiner

Abstract

UNLABELLED: Pediatric Ewing sarcoma is characterized by the expression of chimeric fusions of EWS and ETS family transcription factors, representing a paradigm for studying cancers driven by transcription factor rearrangements. In this study, we describe the somatic landscape of pediatric Ewing sarc...

Subject

Sarcoma

Pediatric cancer

Cancer research

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