Age-Adjusted D-Dimer Cutoff Levels to Rule Out Pulmonary Embolism

Righini, Marc; van Es, Josien; L. den Exter, Paul; Roy, Pierre‐Marie; Verschuren, Franck; Ghuysen, Alexandre; Rutschmann, Olivier; Sanchez, Olivier; Jaffrelot, Morgan; Trinh-Duc, Albert; Le Gall, Catherine; Moustafa, Farès; Principe, Alessandra; A. van Houten, Anja; ten Wolde, Marije; A. Douma, Renée; Hazelaar, Germa; Erkens, Petra; W. van Kralingen, Klaas; J.J.H. Grootenboers, Marco; Durian, Marc; Whitney Cheung, Y.; Meyer, Guy; Bounameaux, Henri; V. Huisman, Menno; W. Kamphuisen, Pieter; Le Gal, Grégoire

doi:10.1001/jama.2014.2135

Public

Age-Adjusted D-Dimer Cutoff Levels to Rule Out Pulmonary Embolism

Published in JAMA • Mar 18, 2014

Authors:

Marc Righini

Josien van Es

Paul L. den Exter

Abstract

IMPORTANCE: D-dimer measurement is an important step in the diagnostic strategy of clinically suspected acute pulmonary embolism (PE), but its clinical usefulness is limited in elderly patients. OBJECTIVE: To prospectively validate whether an age-adjusted D-dimer cutoff, defined as age × 10 in patie...

Subject

Medicine

Cutoff

Pulmonary embolism

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