Pel is a cationic exopolysaccharide that cross-links extracellular DNA in the <i>Pseudomonas aeruginosa</i> biofilm matrix

K. Jennings, Laura; M. Storek, Kelly; E. Ledvina, Hannah; Coulon, Charlène; S. Marmont, Lindsey; Sadovskaya, Irina; R. Secor, Patrick; Shan Tseng, Boo; Scian, Michele; Filloux, Alain; J. Wozniak, Daniel; Lynne Howell, P.; R. Parsek, Matthew

doi:10.1073/pnas.1503058112

Public

Pel is a cationic exopolysaccharide that cross-links extracellular DNA in the Pseudomonas aeruginosa biofilm matrix

Published in Proceedings of the National Academy of Sciences • Aug 26, 2015

Authors:

Laura K. Jennings

Kelly M. Storek

Hannah E. Ledvina

Abstract

Biofilm formation is a complex, ordered process. In the opportunistic pathogen Pseudomonas aeruginosa, Psl and Pel exopolysaccharides and extracellular DNA (eDNA) serve as structural components of the biofilm matrix. Despite intensive study, Pel's chemical structure and spatial localization within m...

Subject

Biofilm

Pseudomonas aeruginosa

Glycosidic bond

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