Pretreatment of Mice with Streptomycin Provides a<i>Salmonella enterica</i>Serovar Typhimurium Colitis Model That Allows Analysis of Both Pathogen and Host

Barthel, Manja; Hapfelmeier, Siegfried; Quintanilla‐Martínez, Leticia; Kremer, Marcus; Rohde, Manfred; Hogardt, Michael; Pfeffer, Klaus; Rüssmann, Holger; Hardt, Wolf‐Dietrich

doi:10.1128/iai.71.5.2839-2858.2003

Public

Pretreatment of Mice with Streptomycin Provides aSalmonella entericaSerovar Typhimurium Colitis Model That Allows Analysis of Both Pathogen and Host

Published in Infection and Immunity • Apr 18, 2003

Authors:

Manja Barthel

Siegfried Hapfelmeier

Leticia Quintanilla‐Martínez

Abstract

Salmonella enterica subspecies 1 serovar Typhimurium is a principal cause of human enterocolitis. For unknown reasons, in mice serovar Typhimurium does not provoke intestinal inflammation but rather targets the gut-associated lymphatic tissues and causes a systemic typhoid-like infection. The lack o...

Subject

Salmonella enterica

Biology

Microbiology

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