Bortezomib or High-Dose Dexamethasone for Relapsed Multiple Myeloma

G. Richardson, Paul; Sonneveld, Pieter; W. Schuster, Michael; Irwin, David; A. Stadtmauer, Edward; Façon, Thierry; Harousseau, Jean‐Luc; Ben‐Yehuda, Dina; Lonial, Sagar; Goldschmidt, Hartmut; Reece, Donna; F. San Miguel, Jesús; Bladé, Joan; Boccadoro, Mario; Cavenagh, Jamie; S. Dalton, William; Boral, Anthony; Esseltine, Dixie; Porter, Jane; P. Schenkein, David; C. Anderson, Kenneth

doi:10.1056/nejmoa043445

Public

Bortezomib or High-Dose Dexamethasone for Relapsed Multiple Myeloma

Published in New England Journal of Medicine • Jun 15, 2005

Authors:

Paul G. Richardson

Pieter Sonneveld

Michael W. Schuster

Abstract

BACKGROUND: This study compared bortezomib with high-dose dexamethasone in patients with relapsed multiple myeloma who had received one to three previous therapies. METHODS: We randomly assigned 669 patients with relapsed myeloma to receive either an intravenous bolus of bortezomib (1.3 mg per squar...

Subject

Medicine

Bortezomib

Dexamethasone

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