Association of Trypanolytic ApoL1 Variants with Kidney Disease in African Americans

Genovese, Giulio; J. Friedman, David; D. Ross, Michael; Lecordier, Laurence; Uzureau, Pierrick; I. Freedman, Barry; W. Bowden, Donald; D. Langefeld, Carl; K. Oleksyk, Taras; L. Uscinski Knob, Andrea; J. Bernhardy, Andrea; J. Hicks, Pamela; W. Nelson, George; Vanhollebeke, Benoit; A. Winkler, Cheryl; B. Kopp, Jeffrey; Pays, Etienne; R. Pollak, Martin

doi:10.1126/science.1193032

Public

Association of Trypanolytic ApoL1 Variants with Kidney Disease in African Americans

Shared by NobleBlocks on Aug 13, 2010 • 12:00 AM UTC

Authors:

Giulio Genovese

David J. Friedman

Michael D. Ross

Abstract

Out of Africa Kidney disease is more common in African Americans than in Americans of European descent, and genetics is likely to be a major contributing factor. Genovese et al. (p. 841 , published online 15 July) now show that African Americans who carry specific sequence variants in a gene on chro...

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