Characterization of Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium Cell Sheets Aiming for Clinical Application

Kamao, Hiroyuki; Mandai, Michiko; Okamoto, Satoshi; Sakai, Noriko; Suga, Akiko; Sugita, Sunao; Kiryu, Junichi; Takahashi, Masayo

doi:10.1016/j.stemcr.2013.12.007

Public

Characterization of Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium Cell Sheets Aiming for Clinical Application

Published in Stem Cell Reports • Jan 23, 2014

Authors:

Hiroyuki Kamao

Michiko Mandai

Satoshi Okamoto

Abstract

Age-related macular degeneration (AMD) causes severe visual impairment due in part to age-dependent impairment of retinal pigment epithelium (RPE). It has been suggested that autologous human induced pluripotent stem cells (hiPSCs) may represent a useful cell source for the generation of graft RPE. ...

Subject

Biology

Retinal pigment epithelium

Induced pluripotent stem cell

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