Ventricular hypertrophy amplifies transmural repolarization dispersion and induces early afterdepolarization

Yan, Gan-Xin; J. Rials, Seth; Wu, Ying; Liu, Tengxian; Xu, Xiaoping; A. Marinchak, Roger; R. Kowey, Peter

doi:10.1152/ajpheart.2001.281.5.h1968

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Ventricular hypertrophy amplifies transmural repolarization dispersion and induces early afterdepolarization

Shared by NobleBlocks on Nov 1, 2001 • 12:00 AM UTC

Authors:

Gan-Xin Yan

Seth J. Rials

Ying Wu

Abstract

The effects of left ventricular hypertrophy (LVH) on the generation of phase 2 early afterdepolarization (EAD) and transmural dispersion of repolarization (TDR) were assessed using arterially perfused rabbit ventricular wedge preparations. Transmembrane action potentials from epicardium, subendocard...

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