Early Compared With Late Radiotherapy in Combined Modality Treatment for Limited Disease Small-Cell Lung Cancer: A London Lung Cancer Group Multicenter Randomized Clinical Trial and Meta-Analysis

Spiro, Stephen; E. James, Lindsay; Rudd, Robin; Trask, Colin; Tobias, Jeffrey; Snee, M.; Gilligan, David; A. Murray, Philip; C Ruiz de Elvira, M; M. O'Donnell, Katy; H. Gower, Nicole; Harper, Peter; Hackshaw, Allan

doi:10.1200/jco.2005.05.3181

Public

Early Compared With Late Radiotherapy in Combined Modality Treatment for Limited Disease Small-Cell Lung Cancer: A London Lung Cancer Group Multicenter Randomized Clinical Trial and Meta-Analysis

Published in Journal of Clinical Oncology • Aug 18, 2006

Authors:

Stephen Spiro

Lindsay E. James

Robin Rudd

Abstract

PURPOSE: To replicate an earlier National Cancer Institute of Canada (NCIC) trial that examined the effect on survival of the timing of thoracic radiotherapy (TRT) in patients with limited disease small-cell lung cancer (SCLC). PATIENTS AND METHODS: Patients received three cycles of cyclophosphamide...

Subject

Medicine

Etoposide

Radiation therapy

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