EZH2 Expression Is Associated With High Proliferation Rate and Aggressive Tumor Subgroups in Cutaneous Melanoma and Cancers of the Endometrium, Prostate, and Breast

Bachmann, Ingeborg; J. Halvorsen, Ole; Collett, Karin; M. Stefansson, Ingunn; Straume, Oddbjørn; A. Haukaas, Svein; B. Salvesen, Helga; P. Otte, Arie; A. Akslen, Lars

doi:10.1200/jco.2005.01.5180

Public

EZH2 Expression Is Associated With High Proliferation Rate and Aggressive Tumor Subgroups in Cutaneous Melanoma and Cancers of the Endometrium, Prostate, and Breast

Published in Journal of Clinical Oncology • Dec 6, 2005

Authors:

Ingeborg Bachmann

Ole J. Halvorsen

Karin Collett

Abstract

PURPOSE: EZH2 is a member of the polycomb group of genes and important in cell cycle regulation. Increased expression of EZH2 has been associated previously with invasive growth and aggressive clinical behavior in prostate and breast cancer, but the relationship with tumor cell proliferation has not...

Subject

Medicine

Prostate

Oncology

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!