The transcription factor Prox1 is a marker for lymphatic endothelial cells in normal and diseased human tissues

Wilting, Jörg; Papoutsi, Maria; Christ, Bodo; H. Nicolaides, K.; S. von Kaisenberg, Constantin; Borges, Jörg; Björn Stark, G.; Alitalo, Kari; I. Tomarev, Stanislav; M. Niemeyer, Charlotte; Rößler, Jochen

doi:10.1096/fj.01-1010fje

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The transcription factor Prox1 is a marker for lymphatic endothelial cells in normal and diseased human tissues

Published in The FASEB Journal • Jun 7, 2002

Authors:

Jörg Wilting

Maria Papoutsi

Bodo Christ

Abstract

Detection of lymphatic endothelal cells (LECs) has been problematic because of the lack of specific markers. The homeobox transcription factor Prox1 is expressed in LECs of murine and avian embryos. We have studied expression of Prox1 in human tissues with immunofluorescence. In 19-wk-old human fetu...

Subject

CD31

Lymphatic system

CD34

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