Once-daily bronchodilators for chronic obstructive pulmonary disease: indacaterol versus tiotropium.

JF, Donohue; C, Fogarty; J, Lötvall; DA, Mahler; H, Worth; A, Yorgancioglu; A, Iqbal; J, Swales; R, Owen; M, Higgins; B, Kramer

doi:10.1164/rccm.200910-1500oc

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Once-daily bronchodilators for chronic obstructive pulmonary disease: indacaterol versus tiotropium.

Shared by NobleBlocks on May 12, 2010 • 12:00 AM UTC

Authors:

Donohue JF

Fogarty C

Lötvall J

Abstract

Rationale Indacaterol is the first once-daily, long-acting inhaled beta(2)-agonist bronchodilator studied in patients with chronic obstructive pulmonary disease (COPD).Objectives To demonstrate greater efficacy of indacaterol versus placebo on FEV(1) at 24 hours post dose (trough) after 12 weeks, to...

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