Immunity-Related Genes and Gene Families in <i>Anopheles gambiae</i>

K. Christophides, George; M. Zdobnov, Evgeny; Barillas‐Mury, Carolina; Birney, Ewan; Blandin, Stéphanie; Blass, Claudia; T. Brey, Paul; H. Collins, Frank; Danielli, Alberto; Dimopoulos, George; Hétru, Charles; Thị Hoa, Ngô; A. Hoffmann, Jules; M. Kanzok, Stefan; Letunić, Ivica; A. Levashina, Elena; G. Loukeris, Thanasis; Lycett, Gareth; Meister, Stephan; Michel, Kristin; F. Moita, Luís; Müller, Hans‐Michael; A. Osta, Mike; M. Paskewitz, Susan; Reichhart, Jean-Marc; Rzhetsky, Andrey; Troxler, Laurent; D. Vernick, Kenneth; Vlachou, Dina; Volz, Jennifer; von Mering, Christian; Xu, Jiannong; Zheng, Liangbiao; Bork, Peer; C. Kafatos, Fotis

doi:10.1126/science.1077136

Public

Immunity-Related Genes and Gene Families in Anopheles gambiae

Published in Science • Oct 3, 2002

Authors:

George K. Christophides

Evgeny M. Zdobnov

Carolina Barillas‐Mury

Abstract

We have identified 242 Anopheles gambiae genes from 18 gene families implicated in innate immunity and have detected marked diversification relative to Drosophila melanogaster. Immune-related gene families involved in recognition, signal modulation, and effector systems show a marked deficit of orth...

Subject

Biology

Gene

Anopheles gambiae

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