Immunity-Related Genes and Gene Families in
                    <i>Anopheles gambiae</i>

K. Christophides, George; Zdobnov, Evgeny; Barillas-Mury, Carolina; Birney, Ewan; Blandin, Stephanie; Blass, Claudia; T. Brey, Paul; H. Collins, Frank; Danielli, Alberto; Dimopoulos, George; Hetru, Charles; T. Hoa, Ngo; A. Hoffmann, Jules; M. Kanzok, Stefan; Letunic, Ivica; A. Levashina, Elena; G. Loukeris, Thanasis; Lycett, Gareth; Meister, Stephan; Michel, Kristin; F. Moita, Luis; Müller, Hans-Michael; A. Osta, Mike; M. Paskewitz, Susan; Reichhart, Jean-Marc; Rzhetsky, Andrey; Troxler, Laurent; D. Vernick, Kenneth; Vlachou, Dina; Volz, Jennifer; von Mering, Christian; Xu, Jiannong; Zheng, Liangbiao; Bork, Peer; C. Kafatos, Fotis

doi:10.1126/science.1077136

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Immunity-Related Genes and Gene Families in Anopheles gambiae

Shared by NobleBlocks on Oct 4, 2002 • 12:00 AM UTC

Authors:

George K. Christophides

Evgeny Zdobnov

Carolina Barillas-Mury

Abstract

We have identified 242 Anopheles gambiae genes from 18 gene families implicated in innate immunity and have detected marked diversification relative to Drosophila melanogaster . Immune-related gene families involved in recognition, signal modulation, and effector systems show a marked deficit of ort...

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