Telaprevir for Previously Untreated Chronic Hepatitis C Virus Infection

M. Jacobson, Ira; G. McHutchison, John; Dusheiko, Geoffrey; M. Di Bisceglie, Adrian; Rajender Reddy, K.; Bzowej, Natalie; Marcellin, Patrick; J. Muir, Andrew; Ferenci, Péter; Flisiak, Robert; George, Jacob; Rizzetto, Mario; Shouval, Daniel; Solà, Ricard; Terg, Rubén; M. Yoshida, Eric; Adda, Nathalie; Bengtsson, Leif; J. Sankoh, Abdul; L. Kieffer, Tara; George, Shelley; S. Kauffman, Robert; Zeuzem, Stefan

doi:10.1056/nejmoa1012912

Public

Telaprevir for Previously Untreated Chronic Hepatitis C Virus Infection

Published in New England Journal of Medicine • Jun 22, 2011

Authors:

Ira M. Jacobson

John G. McHutchison

Geoffrey Dusheiko

Abstract

BACKGROUND: In phase 2 trials, telaprevir, a hepatitis C virus (HCV) genotype 1 protease inhibitor, in combination with peginterferon-ribavirin, as compared with peginterferon-ribavirin alone, has shown improved efficacy, with potential for shortening the duration of treatment in a majority of patie...

Subject

Ribavirin

Telaprevir

Medicine

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