Peripheral-Blood Stem Cells versus Bone Marrow from Unrelated Donors

Anasetti, Claudio; R. Logan, Brent; J. Lee, Stephanie; K. Waller, Edmund; J. Weisdorf, Daniel; R. Wingard, John; Cutler, Corey; Westervelt, Peter; Woolfrey, Ann; Couban, Stephen; Ehninger, Gerhard; Johnston, Laura; T. Maziarz, Richard; A. Pulsipher, Michael; Porter, David; Mineishi, Shin; M. McCarty, John; P. Khan, Shakila; Anderlini, Paolo; Bensinger, William; F. Leitman, Susan; D. Rowley, Scott; Bredeson, Christopher; L. Carter, Shelly; M. Horowitz, Mary; L. Confer, Dennis

doi:10.1056/nejmoa1203517

Public

Peripheral-Blood Stem Cells versus Bone Marrow from Unrelated Donors

Published in New England Journal of Medicine • Oct 18, 2012

Authors:

Claudio Anasetti

Brent R. Logan

Stephanie J. Lee

Abstract

BACKGROUND: Randomized trials have shown that the transplantation of filgrastim-mobilized peripheral-blood stem cells from HLA-identical siblings accelerates engraftment but increases the risks of acute and chronic graft-versus-host disease (GVHD), as compared with the transplantation of bone marrow...

Subject

Medicine

Bone marrow

Transplantation

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