Reduced Insulinotropic Effect of Gastric Inhibitory Polypeptide in First-Degree Relatives of Patients With Type 2 Diabetes

J. Meier, Juris; Hücking, Katrin; J. Holst, Jens; F. Deacon, Carolyn; Schmiegel, Wolff; A. Nauck, Michael

doi:10.2337/diabetes.50.11.2497

Public

Reduced Insulinotropic Effect of Gastric Inhibitory Polypeptide in First-Degree Relatives of Patients With Type 2 Diabetes

Published in Diabetes • Nov 1, 2001

Authors:

Juris J. Meier

Katrin Hücking

Jens J. Holst

Abstract

In patients with type 2 diabetes, gastric inhibitory polypeptide (GIP) has lost much of its insulinotropic activity. Whether this is similar in first-degree relatives of patients with type 2 diabetes is unknown. A total of 21 first-degree relatives, 10 patients with type 2 diabetes, and 10 control s...

Subject

First-degree relatives

Internal medicine

Diabetes mellitus

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