Paclitaxel plus Bevacizumab versus Paclitaxel Alone for Metastatic Breast Cancer

D. Miller, Kathy; Wang, Molin; R. Gralow, Julie; N. Dickler, Maura; Cobleigh, Melody; A. Perez, Edith; Shenkier, Tamara; Cella, David; E. Davidson, Nancy

doi:10.1056/nejmoa072113

Public

Paclitaxel plus Bevacizumab versus Paclitaxel Alone for Metastatic Breast Cancer

Published in New England Journal of Medicine • Dec 26, 2007

Authors:

Kathy D. Miller

Molin Wang

Julie R. Gralow

Abstract

BACKGROUND: In an open-label, randomized, phase 3 trial, we compared the efficacy and safety of paclitaxel with that of paclitaxel plus bevacizumab, a monoclonal antibody against vascular endothelial growth factor, as initial treatment for metastatic breast cancer. METHODS: We randomly assigned pati...

Subject

Medicine

Paclitaxel

Bevacizumab

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