Randomized placebo-controlled trial of prednisone for paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome

Meintjes, Graeme; J. Wilkinson, Robert; Morroni, Chelsea; J. Pepper, Dominique; Rebe, Kevin; X. Rangaka, Molebogeng; Oni, Tolu; Maartens, Gary

doi:10.1097/qad.0b013e32833dfc68

Public

Randomized placebo-controlled trial of prednisone for paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome

Published in AIDS • Aug 31, 2010

Authors:

Graeme Meintjes

Robert J. Wilkinson

Chelsea Morroni

Abstract

OBJECTIVE: Paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is a frequent complication of antiretroviral therapy in resource-limited countries. We aimed to assess whether a 4-week course of prednisone would reduce morbidity in patients with paradoxical TB-IRI...

Subject

Medicine

Prednisone

Interquartile range

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