Influenza A viruses target type II pneumocytes in the human lung.

VK, Weinheimer; A, Becher; M, Tönnies; G, Holland; J, Knepper; TT, Bauer; P, Schneider; J, Neudecker; JC, Rückert; K, Szymanski; B, Temmesfeld-Wollbrueck; AD, Gruber; N, Bannert; N, Suttorp; S, Hippenstiel; T, Wolff; AC, Hocke

doi:10.1093/infdis/jis455

Public

Influenza A viruses target type II pneumocytes in the human lung.

Shared by NobleBlocks on Jul 24, 2012 • 12:00 AM UTC

Authors:

Weinheimer VK

Becher A

Tönnies M

Abstract

Background Highly pathogenic avian H5N1 influenza viruses preferentially infect alveolar type II pneumocytes in human lung. However, it is unknown whether this cellular tropism contributes to high viral virulence because the primary target cells of other influenza viruses have not been systematicall...

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