Infliximab, Azathioprine, or Combination Therapy for Crohn's Disease

Colombel, Jean‐Frédéric; J. Sandborn, William; Reinisch, Walter; J. Mantzaris, Gerassimos; Kornbluth, Asher; Rachmilewitz, Daniel; Lichtiger, Simon; D’Haens, Geert; H. Diamond, Robert; L. Broussard, Delma; L. Tang, Kezhen; Janneke van der Woude, C.; Rutgeerts, Paul

doi:10.1056/nejmoa0904492

Public

Infliximab, Azathioprine, or Combination Therapy for Crohn's Disease

Published in New England Journal of Medicine • Apr 14, 2010

Authors:

Jean‐Frédéric Colombel

William J. Sandborn

Walter Reinisch

Abstract

BACKGROUND: The comparative efficacy and safety of infliximab and azathioprine therapy alone or in combination for Crohn's disease are unknown. METHODS: In this randomized, double-blind trial, we evaluated the efficacy of infliximab monotherapy, azathioprine monotherapy, and the two drugs combined i...

Subject

Medicine

Infliximab

Azathioprine

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