Her-2/neu analysis in archival tissue samples of human breast cancer: comparison of immunohistochemistry and fluorescence in situ hybridization.

A, Lebeau; D, Deimling; C, Kaltz; A, Sendelhofert; A, Iff; B, Luthardt; M, Untch; U, Löhrs

doi:10.1200/jco.2001.19.2.354

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Her-2/neu analysis in archival tissue samples of human breast cancer: comparison of immunohistochemistry and fluorescence in situ hybridization.

Shared by NobleBlocks on Jan 1, 2001 • 12:00 AM UTC

Authors:

Lebeau A

Deimling D

Kaltz C

Abstract

Purpose The objective of our study was to compare the methods used in the literature to analyze HER-2/neu status on archival breast cancer tissue. Therefore, a series of antibodies was evaluated to assess their immunohistochemical (IHC) sensitivity in correlation to gene amplification determined by ...

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