Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing

R. Tice, Raymond; Agurell, Eva; Anderson, Diana; Burlinson, Brian; Hartmann, Andreas; Kobayashi, Hiroshi; Miyamae, Youichi; Rojas, Emilio; Ryu, Jae‐Chun; F. Sasaki, Yū

doi:10.1002/(sici)1098-2280(2000)35:3<206::aid-em8>3.0.co;2-j

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Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing

Published in Environmental and Molecular Mutagenesis • Jun 6, 2000

Authors:

Raymond R. Tice

Eva Agurell

Diana Anderson

Abstract

Atthe International Workshop on Genotoxicity Test Procedures (IWGTP) held in Washington, DC, March 25-26, 1999, an expert panel met to develop guidelines for the use of the single-cell gel (SCG)/Comet assay in genetic toxicology. The expert panel reached a consensus that the optimal version of the C...

Subject

Comet assay

Genotoxicity

DNA damage

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