Randomized Trial of Radiotherapy Plus Concurrent-Adjuvant Chemotherapy vs Radiotherapy Alone for Regionally Advanced Nasopharyngeal Carcinoma

W. M. Lee, A.; Tung, Shui‐Yi; Chua, Dtt; K.C. Ngan, Roger; J. Chappell, Richard; Tung, Raymond; Siu, L.L.; Tong Ng, Wai; Sze, Wai-Man; Au, G.K.H.; C. K. Law, S.; O’Sullivan, Brian; Yau, T.K.; Leung, To‐Wai; S. K. Au, Joseph; Sze, W.M.; Choi, Cheuk‐Wai; K. Fung, K.; T. Lau, J.; Lau, W.H.

doi:10.1093/jnci/djq258

Public

Randomized Trial of Radiotherapy Plus Concurrent-Adjuvant Chemotherapy vs Radiotherapy Alone for Regionally Advanced Nasopharyngeal Carcinoma

Published in JNCI Journal of the National Cancer Institute • Jul 15, 2010

Authors:

A. W. M. Lee

Shui‐Yi Tung

Dtt Chua

Abstract

BACKGROUND: Current practice of adding concurrent-adjuvant chemotherapy to radiotherapy (CRT) for treating advanced nasopharyngeal carcinoma is based on the Intergroup-0099 Study published in 1998. However, the outcome for the radiotherapy-alone (RT) group in that trial was substantially poorer than...

Subject

Medicine

Nasopharyngeal carcinoma

Radiation therapy

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