Ki67 Index, HER2 Status, and Prognosis of Patients With Luminal B Breast Cancer

C.U. Cheang, Maggie; Chia, Stephen; Voduc, David; Gao, Dongxia; Leung, Samuel; Snider, Jacqueline; Watson, Mark; R. Davies, Sherri; S. Bernard, Philip; S. Parker, Joel; M. Perou, Charles; J. Ellis, Matthew; O. Nielsen, Torsten

doi:10.1093/jnci/djp082

Public

Ki67 Index, HER2 Status, and Prognosis of Patients With Luminal B Breast Cancer

Published in JNCI Journal of the National Cancer Institute • May 12, 2009

Authors:

Maggie C.U. Cheang

Stephen Chia

David Voduc

Abstract

BACKGROUND: Gene expression profiling of breast cancer has identified two biologically distinct estrogen receptor (ER)-positive subtypes of breast cancer: luminal A and luminal B. Luminal B tumors have higher proliferation and poorer prognosis than luminal A tumors. In this study, we developed a cli...

Subject

Breast cancer

Immunohistochemistry

Medicine

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