Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer

Ribic, Christine; J. Sargent, Daniel; J. Moore, Malcolm; N. Thibodeau, Stephen; J. French, Amy; M. Goldberg, Richard; R. Hamilton, Stanley; Laurent‐Puig, Pierre; Gryfe, Robert; E. Shepherd, Lois; Tu, Dongsheng; Redston, Mark; Gallinger, Steven

doi:10.1056/nejmoa022289

Public

Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer

Published in New England Journal of Medicine • Jul 16, 2003

Authors:

Christine Ribic

Daniel J. Sargent

Malcolm J. Moore

Abstract

BACKGROUND: Colon cancers with high-frequency microsatellite instability have clinical and pathological features that distinguish them from microsatellite-stable tumors. We investigated the usefulness of microsatellite-instability status as a predictor of the benefit of adjuvant chemotherapy with fl...

Subject

Microsatellite instability

Hazard ratio

Medicine

Research Assistant

AI chat, annotations, notes & similar papers

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!