Assessment of cumulative evidence on genetic associations: interim guidelines

P. A. Ioannidis, John; Boffetta, Paolo; Little, Julian; R O'Brien, T.; G. Uitterlinden, André; Vineis, Paolo; J. Balding, David; P. Chokkalingam, Anand; M. Dolan, Siobhan; Dana Flanders, W.; P. T. Higgins, Julian; I. McCarthy, Mark; H. McDermott, David; P. Page, Grier; R. Rebbeck, Timothy; Seminara, Daniela; J. Khoury, Muin

doi:10.1093/ije/dym159

Public

Assessment of cumulative evidence on genetic associations: interim guidelines

Published in International Journal of Epidemiology • Sep 26, 2007

Authors:

John P. A. Ioannidis

Paolo Boffetta

Julian Little

Abstract

Established guidelines for causal inference in epidemiological studies may be inappropriate for genetic associations. A consensus process was used to develop guidance criteria for assessing cumulative epidemiologic evidence in genetic associations. A proposed semi-quantitative index assigns three le...

Subject

Interim

Epidemiology

Credibility

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