Stimuli‐Responsive Controlled Drug Release from a Hollow Mesoporous Silica Sphere/Polyelectrolyte Multilayer Core–Shell Structure

Zhu, Yufang; Shi, Jianlin; Shen, Weihua; Dong, Xiaoping; Feng, Jingwei; Ruan, Meilin; Li, Yongsheng

doi:10.1002/anie.200501500

Public

Stimuli‐Responsive Controlled Drug Release from a Hollow Mesoporous Silica Sphere/Polyelectrolyte Multilayer Core–Shell Structure

Published in Angewandte Chemie International Edition • Jul 14, 2005

Authors:

Yufang Zhu

Jianlin Shi

Weihua Shen

Abstract

Keeping drugs under control: Hydrothermally stable, hollow mesoporous silica spheres have a high drug storage capacity, and polyelectrolyte multilayers coated on the spheres act as a switch for drug release which is controlled by the pH or ionic strength of the release medium. The picture shows the ...

Subject

Polyelectrolyte

Mesoporous silica

Shell (structure)

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