Studies on Treatment of Acute Promyelocytic Leukemia With Arsenic Trioxide: Remission Induction, Follow-Up, and Molecular Monitoring in 11 Newly Diagnosed and 47 Relapsed Acute Promyelocytic Leukemia Patients

Niu, Chao; Yan, Hua; Yu, Ting; Sun, Huiping; Liu, Jianxiang; Xiu-song, LI; Wu, Wen; Zhang, Fenqin; Chen, Yu; Zhou, Li; Li, Junmin; Zeng, Xiao-ying; Ou Yang, Ren-Rong; Yuan, Mi-Man; Ren, Mei-Yu; Feng-ying, Gu; Cao, Qi; Gu, Bo-Wei; Su, Xinying; Chen, Guoqiang; Xiong, Shu-Min; Zhang, Ting-dong; Waxman, Samuel; Wang, Zhenyi; Chen, Zhu; Hu, Jiong; Shen, Zhixiang; Chen, Sai‐Juan

doi:10.1182/blood.v94.10.3315.422k16_3315_3324

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Studies on Treatment of Acute Promyelocytic Leukemia With Arsenic Trioxide: Remission Induction, Follow-Up, and Molecular Monitoring in 11 Newly Diagnosed and 47 Relapsed Acute Promyelocytic Leukemia Patients

Published in Blood • Nov 15, 1999

Authors:

Chao Niu

Hua Yan

Ting Yu

Abstract

Fifty-eight acute promyelocytic leukemia (APL) patients (11 newly diagnosed and 47 relapsed) were studied for arsenic trioxide (As2O3) treatment. Clinical complete remission (CR) was obtained in 8 of 11 (72.7%) newly diagnosed cases. However, As2O3 treatment resulted in hepatic toxicity in 7 cases i...

Subject

Acute promyelocytic leukemia

Arsenic trioxide

Medicine

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