Opsonic phagocytosis of Plasmodium falciparummerozoites: mechanism in human immunity and a correlate of protection against malaria

Osier, Faith; Feng, Gaoqian; J. Boyle, Michelle; Langer, Christine; Zhou, Jingling; S. Richards, Jack; J. McCallum, Fiona; Reiling, Linda; Jaworowski, Anthony; F. Anders, Robin; Marsh, Kevin; G. Beeson, James

doi:10.1186/1741-7015-12-108

Public

Opsonic phagocytosis of Plasmodium falciparummerozoites: mechanism in human immunity and a correlate of protection against malaria

Published in BMC Medicine • Jul 1, 2014

Authors:

Faith Osier

Gaoqian Feng

Michelle J. Boyle

Abstract

BACKGROUND: An understanding of the mechanisms mediating protective immunity against malaria in humans is currently lacking, but critically important to advance the development of highly efficacious vaccines. Antibodies play a key role in acquired immunity, but the functional basis for their protect...

Subject

Opsonin

Phagocytosis

Malaria

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