Tumor-Infiltrating FOXP3
                    <sup>+</sup>
                    T Regulatory Cells Show Strong Prognostic Significance in Colorectal Cancer

Salama, Paul; Phillips, Michael; Grieu, Fabienne; Morris, Melinda; Zeps, Nik; Joseph, David; Platell, Cameron; Iacopetta, Barry

doi:10.1200/jco.2008.18.7229

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Tumor-Infiltrating FOXP3 + T Regulatory Cells Show Strong Prognostic Significance in Colorectal Cancer

Shared by NobleBlocks on Jan 10, 2009 • 12:00 AM UTC

Authors:

Paul Salama

Michael Phillips

Fabienne Grieu

Abstract

Purpose To determine the prognostic significance of FOXP3 + lymphocyte (Treg) density in colorectal cancer compared with conventional histopathologic features and with CD8 + and CD45RO + lymphocyte densities. Patients and Methods Tissue microarrays and immunohistochemistry were used to assess the de...

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