5′ tRNA halves are present as abundant complexes in serum, concentrated in blood cells, and modulated by aging and calorie restriction

M. Dhahbi, Joseph; R. Spindler, Stephen; Atamna, Hani; Yamakawa, Amy; Boffelli, Dario; L. Mote, Patricia; I. K. Martin, David

doi:10.1186/1471-2164-14-298

Public

5′ tRNA halves are present as abundant complexes in serum, concentrated in blood cells, and modulated by aging and calorie restriction

Published in BMC Genomics • Jan 1, 2013

Authors:

Joseph M. Dhahbi

Stephen R. Spindler

Hani Atamna

Abstract

BACKGROUND: Small RNAs complex with proteins to mediate a variety of functions in animals and plants. Some small RNAs, particularly miRNAs, circulate in mammalian blood and may carry out a signaling function by entering target cells and modulating gene expression. The subject of this study is a set ...

Subject

Biology

Transfer RNA

Microvesicles

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