Hepatitis B Virus Strains with Mutations in the Core Promoter in Patients with Fulminant Hepatitis

Sato, Shunichi; Suzuki, Kazuyuki; Akahane, Yoshihiro; Akamatsu, Koichi; Akiyama, Kenji; Yunomura, Kazuhiro; Tsuda, Fumio; Tanaka, Takeshi; Okamoto, Hiroaki; Miyakawa, Yuzo; Mayumi, Makoto

doi:10.7326/0003-4819-122-4-199502150-00001

Public

Hepatitis B Virus Strains with Mutations in the Core Promoter in Patients with Fulminant Hepatitis

Published in Annals of Internal Medicine • Feb 15, 1995

Authors:

Shunichi Sato

Kazuyuki Suzuki

Yoshihiro Akahane

Abstract

OBJECTIVE: Fulminant hepatitis B can be induced by hepatitis B virus (HBV) strains with mutations in the precore region that cannot encode hepatitis B e antigen (HBeAg). Such mutations are rarely seen in HBV DNA clones from patients with fulminant hepatitis B in the United States and France. Thus, t...

Subject

Fulminant hepatitis

HBeAg

Virology

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