Mutations in the Genes for Oocyte-Derived Growth Factors GDF9 and BMP15 Are Associated with Both Increased Ovulation Rate and Sterility in Cambridge and Belclare Sheep (Ovis aries)1

P. Hanrahan, J.; M. Gregan, Scott; Mulsant, Philippe; P. Mullen, Michael; H. Davis, G.; Powell, Richard; Galloway, Susan

doi:10.1095/biolreprod.103.023093

Public

Mutations in the Genes for Oocyte-Derived Growth Factors GDF9 and BMP15 Are Associated with Both Increased Ovulation Rate and Sterility in Cambridge and Belclare Sheep (Ovis aries)1

Published in Biology of Reproduction • Apr 1, 2004

Authors:

J. P. Hanrahan

Scott M. Gregan

Philippe Mulsant

Abstract

Belclare and Cambridge are prolific sheep breeds, the origins of which involved selecting ewes with exceptionally high litter size records from commercial flocks. The variation in ovulation rate in both breeds is consistent with segregation of a gene (or genes) with a large effect on this trait. Ste...

Subject

Bone morphogenetic protein 15

Biology

Ovulation

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