A targeted functional RNA interference screen uncovers glypican 5 as an entry factor for hepatitis B and D viruses

R. Verrier, Éloi; C. Colpitts, Che; Bach, C; Heydmann, Laura; Weiss, Amélie; Renaud, Mickaël; Durand, Sarah; Habersetzer, François; Durantel, David; Abou-Jaoudé, Georges; M. López Ledesma, Maria; J. Felmlee, Daniel; Soumillon, Magali; Croonenborghs, Tom; Pochet, Nathalie; Nassal, Michael; Schuster, Catherine; Brino, Laurent; Sureau, Camille; B. Zeisel, Mirjam; F. Baumert, Thomas

doi:10.1002/hep.28013

Public

A targeted functional RNA interference screen uncovers glypican 5 as an entry factor for hepatitis B and D viruses

Published in Hepatology • Jul 30, 2015

Authors:

Éloi R. Verrier

Che C. Colpitts

C Bach

Abstract

UNLABELLED: Chronic hepatitis B and D infections are major causes of liver disease and hepatocellular carcinoma worldwide. Efficient therapeutic approaches for cure are absent. Sharing the same envelope proteins, hepatitis B virus and hepatitis delta virus use the sodium/taurocholate cotransporting ...

Subject

Glypican 3

Virology

RNA interference

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