Exercise-Induced Irisin Secretion Is Independent of Age or Fitness Level and Increased Irisin May Directly Modulate Muscle Metabolism Through AMPK Activation

Young Huh, Joo; Mougios, Vassilis; Kabasakalis, Athanasios; G. Fatouros, Ioannis; Siopi, Aikaterina; Douroudos, Ioannis; Filippaios, Andreas; Panagiotou, Grigorios; Park, Kyung‐Hee; S. Mantzoros, Christos

doi:10.1210/jc.2014-1437

Public

Exercise-Induced Irisin Secretion Is Independent of Age or Fitness Level and Increased Irisin May Directly Modulate Muscle Metabolism Through AMPK Activation

Published in The Journal of Clinical Endocrinology & Metabolism • Aug 13, 2014

Authors:

Joo Young Huh

Vassilis Mougios

Athanasios Kabasakalis

Abstract

CONTEXT: Irisin has been proposed to be a myokine mediating the effect of exercise on adipocyte browning. The physiology of irisin in humans is not completely understood. OBJECTIVE: To study the physiology of irisin in healthy individuals with different age and fitness levels and to explore the dire...

Subject

Myokine

Endocrinology

Internal medicine

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