A Large Outbreak ofClostridium difficile–Associated Disease with an Unexpected Proportion of Deaths and Colectomies at a Teaching Hospital Following Increased Fluoroquinolone Use

A. Muto, Carlene; Pokrywka, Marian; A. Shutt, Kathleen; B. Mendelsohn, Aaron; Nouri, Kathy; Posey, Kathy; L. Roberts, Terri; Croyle, Karen; Krystoflak, Sharon; Patel-Brown, Sujata; William Pasculle, A.; L. Paterson, David; Saul, Melissa; H. Harrison, Lee

doi:10.1086/502539

Public

A Large Outbreak ofClostridium difficile–Associated Disease with an Unexpected Proportion of Deaths and Colectomies at a Teaching Hospital Following Increased Fluoroquinolone Use

Published in Infection Control and Hospital Epidemiology • Mar 1, 2005

Authors:

Carlene A. Muto

Marian Pokrywka

Kathleen A. Shutt

Abstract

BACKGROUND AND OBJECTIVE: Fluoroquinolones have not been frequently implicated as a cause of Clostridium difficile outbreaks. Nosocomial C. difficile infections increased from 2.7 to 6.8 cases per 1000 discharges (P < .001). During the first 2 years of the outbreak, there were 253 nosocomial C. diff...

Subject

Outbreak

Medicine

Clostridium difficile

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