Mutation of the Stargardt Disease Gene ( <i>ABCR</i> ) in Age-Related Macular Degeneration

Allikmets, Rando; F. Shroyer, Noah; Singh, Nanda; M. Seddon, Johanna; A. Lewis, Richard; S. Bernstein, Paul; Peiffer, Andy; A. Zabriskie, Norman; Li, Yixin; Hutchinson, Amy; Dean, Michael; R. Lupski, James; Leppert, Mark

doi:10.1126/science.277.5333.1805

Public

Mutation of the Stargardt Disease Gene ( ABCR ) in Age-Related Macular Degeneration

Published in Science • Sep 19, 1997

Authors:

Rando Allikmets

Noah F. Shroyer

Nanda Singh

Abstract

Age-related macular degeneration (AMD) is the leading cause of severe central visual impairment among the elderly and is associated both with environmental factors such as smoking and with genetic factors. Here, 167 unrelated AMD patients were screened for alterations in ABCR, a gene that encodes a ...

Subject

Stargardt disease

ABCA4

Macular degeneration

Finding related papers...

Discussions

(0)

No comments yet

Be the first to share your thoughts!